カイジ(槐耳)はサルノコシカケ科のキノコの一種である。槐蛾、槐栓菌ともいう。学名Trametes robiniophila Murr.です。
中国では、カイジ菌糸体エキスを利用して開発した国家級一類抗がん新薬カイジ(槐耳)顆粒、登録商標金克です。中国及び海外での英字論文はカイジ(槐耳)顆粒に対し、一般表記Huaier,jinkeですが、Huaierは槐耳の中国語の発音で、Jinkeは金克中国語の発音です。カイジは槐耳の日本語読み方で、中国での薬登録番号Z-20000109(State Drug Administration License of China No Z-20000109)です、カイジは多数の臨床論文が発表されています。
カイジ(槐耳)については、中国のみならず、日本、米国等でも多数の研究論文が発表されています。
Huaier extract synergizes with tamoxifen to induce autophagy and apoptosis in ER-positive breast cancer cells(TAMとカイ栓菌投与による乳がん細胞のアポトーシスについて.pdf)
DOI: 10.18632/oncotarget.8303 March 23, 2016
腫瘍以外の分野でのカイ栓菌の応用.pdf
日本補完代替医療学会誌 第11巻 第1号 (2014年3月)
Protective effects of Huang Qi Huai granules on adriamycin nephrosis in rats.pdf
Pediatr Nephrol (2011) 26:905?913
Inhibitory Effect of Extract of Fungi of Huaier on Hepatocellular Carcinoma Cells.pdf
J Huazhong Univ Sci Technol[Med Sci]
Apoptosis-inducing effect of Jinke on Molt-4 cells and its mechanism.pdf
Chinese-German Journal of Clinical Oncology August 2008, Vol. 7, No. 8, P487?P491
Anticancer Effect of PS-T on the Experimental Hepatocellular Carcinoma.pdf
The Chinese-German Journal of Clinical Oncology Mar. 2004, Vol.3, No.1 P55?P59
Effects of Huaier aqueous extract on proliferation and apoptosis in the melanomacell line A875.pdf
ONCOLOGY LETTERS 5: 1171-1176, 2013 Received October 13, 2012; Accepted January 4, 2013
A polysaccharide from the fungi of Huaier exhibits anti-tumor potential and immunomodulatory effects.pdf
Carbohydrate Polymers 92 (2013) 577? 582
Huaier Aqueous Extract Inhibits Ovarian Cancer Cell Motility via the Catenin Pathway.pdf
PLOS ONE | 14 May 2013 | Volume 8 | Issue 5 | e63731
Huaier aqueous extract suppresses human breast cancer cell proliferation through inhibition of estrogen receptor signaling.pdf
INTERNATIONAL JOURNAL OF ONCOLOGY July 2013 Volume 43 Number 1
Huaier aqueous extract inhibits proliferation of breast cancer cells by inducing apoptosis.pdf
Cancer Sci | 2010 | 9 Japanese Cancer Association
Huaier aqueous extract suppresses human breast cancer cell proliferation through inhibition of estrogen receptor α signaling.pdf
INTERNATIONAL JOURNAL OF ONCOLOGY
Role of Huaier Extract as a Promising Anticancer Drug.pdf
Adaptive Medicine 4(2): 2012
Huai Qi Huang ameliorates proteinuria and hematuria in mild IgA nephropathy patientsA prospective randomized controlled study.pdf
Journal of the Formosan Medical Association (2013) 112, 766e772
The anticancer effect of Huaier(カイ栓菌の抗がん作用(Review).pdf)
ONCOLOGY REPORTS (2013) Received December 11, 2014; Accepted March 24, 2015
Huaier aqueous extract induces apoptosis of human fibrosarcoma HT1080 cells through the mitochondrial pathway(カイ栓菌の肉腫論文.pdf)
ONCOLOGY LETTERS 9: 1590-1596, 2015 Received April 9, 2014; Accepted January 8, 2015
Anti-angiogenic and antitumor activities of Huaier aqueous extract(カイ栓菌の抗血管形成.pdf)
ONCOLOGY REPORTS 28: 1167-1175, 2012 Received June 12, 2012; Accepted July 13, 2012
Huaier Cream Protects against Adriamycin-Induced Nephropathy by Restoring Mitochondrial Function via PGC-1α Upregulation(カイ栓菌の腎症の保護.pdf)
Hindawi Publishing Corporation PPAR Research Volume 2015, Article ID 720383, 11 pages http://dx.doi.org/10.1155/2015/720383
Huaier Extract Induces Autophagic Cell Death by Inhibiting the mTOR S6K Pathway in Breast Cancer Cells.pdf
PLOS ONE | DOI:10.1371/journal.pone.0131771 July 2, 2015
The anticancer effect of Huaier (Review)(カイ栓菌の抗がん作用.pdf)
ONCOLOGY REPORTS Received December 11, 2014; Accepted March 24, 2015 DOI: 10.3892/or.2015.3950
Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway(カイ栓菌の肝臓がん細胞の論文.pdf)
Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Article ID 171356
Preliminary study of Huai Qi Huang granules delay the development of primary glomerular diseases in human(カイ栓菌の腎症の保護.pdf)
2014 Informa Healthcare USA, Inc. DOI: 10.3109/0886022X.2014.952746